Drug Name: | Ranolazine |
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Drug Class: | Anti-anginal agent |
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Mechanism of Action: | - Inhibits late sodium current in cardiac myocytes
- Reduces intracellular calcium overload
- Improves diastolic relaxation
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Use: | - Treatment of chronic angina pectoris
- May be used in combination with other anti-anginal agents
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Side Effects: | - Nausea
- Dizziness
- Headache
- Constipation
- QT prolongation
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Contraindications: | - Hypersensitivity to ranolazine
- Severe hepatic impairment
- Use of strong CYP3A inhibitors
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Specialty: | - Cardiology
- Internal Medicine
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