Drug Name:Riluzole
Drug Class:Glutamate modulator
Mechanism of Action:
  • Inhibits glutamate release
  • Blocks voltage-dependent sodium channels
  • Modulates NMDA and AMPA receptors
Use:
  • Treatment of amyotrophic lateral sclerosis (ALS)
  • May have neuroprotective effects in other neurological disorders
Side Effects:
  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Liver function abnormalities
Contraindications:
  • Hypersensitivity to riluzole
  • Severe hepatic impairment
Specialty:
  • Neurology
  • Pulmonology