Drug Name: | Rituximab |
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Drug Class: | Monoclonal antibody |
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Mechanism of Action: | Targets CD20 antigen on B cells, leading to B cell depletion |
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Use: | - Non-Hodgkin's lymphoma
- Chronic lymphocytic leukemia
- Rheumatoid arthritis
- Granulomatosis with polyangiitis
- Microscopic polyangiitis
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Side Effects: | - Infusion reactions
- Infections
- Hepatitis B reactivation
- Cardiac arrhythmias
- Tumor lysis syndrome
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Contraindications: | - Hypersensitivity to rituximab
- Active severe infections
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Specialty: | - Oncology
- Rheumatology
- Immunology
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