Drug Name:Rituximab
Drug Class:Monoclonal antibody
Mechanism of Action:Targets CD20 antigen on B cells, leading to B cell depletion
Use:
  • Non-Hodgkin's lymphoma
  • Chronic lymphocytic leukemia
  • Rheumatoid arthritis
  • Granulomatosis with polyangiitis
  • Microscopic polyangiitis
Side Effects:
  • Infusion reactions
  • Infections
  • Hepatitis B reactivation
  • Cardiac arrhythmias
  • Tumor lysis syndrome
Contraindications:
  • Hypersensitivity to rituximab
  • Active severe infections
Specialty:
  • Oncology
  • Rheumatology
  • Immunology