| Drug Name: | Selegiline |
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| Drug Class: | Monoamine oxidase inhibitor (MAOI) |
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| Mechanism of Action: | - Selective and irreversible inhibitor of MAO-B at low doses
- Non-selective and irreversible inhibitor of MAO-A and MAO-B at high doses
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| Use: | - Treatment of Parkinson's disease
- Adjunctive therapy in major depressive disorder
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| Side Effects: | - Insomnia
- Nausea
- Dry mouth
- Dizziness
- Headache
- Hypertension
- Hallucinations
- Confusion
- Agitation
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| Contraindications: | - Hypersensitivity to selegiline
- Concomitant use with other MAOIs
- Concomitant use with meperidine
- History of cerebrovascular disease
- History of hypertension
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| Specialty: | |
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