| Drug Name: | Setmelanotide |
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| Drug Class: | Melanocortin-4 receptor (MC4R) agonist |
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| Mechanism of Action: | Activates the MC4R in the brain, which regulates appetite and energy balance |
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| Use: | - Treatment of obesity caused by genetic defects in the MC4R pathway
- Management of severe obesity in patients with POMC, PCSK1, or LEPR deficiency
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| Side Effects: | - Nausea
- Vomiting
- Injection site reactions
- Hyperpigmentation
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| Contraindications: | - Hypersensitivity to setmelanotide or any component of the formulation
- Pregnancy and breastfeeding
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| Specialty: | |
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