| Drug Name: | Sildenafil |
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| Drug Class: | Phosphodiesterase type 5 (PDE5) inhibitor |
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| Mechanism of Action: | - Inhibits PDE5, leading to increased levels of cyclic guanosine monophosphate (cGMP)
- Relaxes smooth muscle in the corpus cavernosum, leading to increased blood flow and penile erection
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| Use: | - Treatment of erectile dysfunction (ED)
- Treatment of pulmonary arterial hypertension (PAH)
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| Side Effects: | - Headache
- Flushing
- Dyspepsia
- Nasal congestion
- Impaired vision
- Hearing loss
- Priapism
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| Contraindications: | - Concomitant use with nitrates or nitric oxide donors
- Hypersensitivity to sildenafil or any component of the formulation
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| Specialty: | - Urology
- Pulmonology
- Cardiology
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