Drug Name:Sitagliptin
Drug Class:Dipeptidyl peptidase-4 (DPP-4) inhibitor
Mechanism of Action:
  • Inhibits the enzyme DPP-4, which breaks down incretin hormones
  • Increases insulin secretion and decreases glucagon secretion
Use:
  • Type 2 diabetes mellitus
Side Effects:
  • Upper respiratory tract infection
  • Headache
  • Hypoglycemia
  • Pancreatitis
Contraindications:
  • Type 1 diabetes mellitus
  • Diabetic ketoacidosis
  • History of pancreatitis
Specialty:
  • Endocrinology
  • Internal Medicine