Drug Name:Suxamethonium
Drug Class:Depolarizing neuromuscular blocker
Mechanism of Action:
  • Binds to nicotinic acetylcholine receptors at the neuromuscular junction
  • Causes depolarization and muscle contraction
  • Rapidly metabolized by plasma cholinesterase
Use:
  • Facilitates endotracheal intubation
  • Muscle relaxation during surgery
  • Emergency treatment of laryngospasm
Side Effects:
  • Bradycardia
  • Hypotension
  • Hyperkalemia
  • Malignant hyperthermia
  • Muscle pain
  • Prolonged paralysis
Contraindications:
  • Known hypersensitivity to the drug
  • Personal or family history of malignant hyperthermia
  • Severe burns or trauma
  • Neuromuscular disorders
Specialty:
  • Anesthesiology
  • Emergency medicine
  • Critical care medicine