Drug Name: | Suxamethonium |
---|
Drug Class: | Depolarizing neuromuscular blocker |
---|
Mechanism of Action: | - Binds to nicotinic acetylcholine receptors at the neuromuscular junction
- Causes depolarization and muscle contraction
- Rapidly metabolized by plasma cholinesterase
|
---|
Use: | - Facilitates endotracheal intubation
- Muscle relaxation during surgery
- Emergency treatment of laryngospasm
|
---|
Side Effects: | - Bradycardia
- Hypotension
- Hyperkalemia
- Malignant hyperthermia
- Muscle pain
- Prolonged paralysis
|
---|
Contraindications: | - Known hypersensitivity to the drug
- Personal or family history of malignant hyperthermia
- Severe burns or trauma
- Neuromuscular disorders
|
---|
Specialty: | - Anesthesiology
- Emergency medicine
- Critical care medicine
|
---|