Drug Name: | Tadalafil |
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Drug Class: | Phosphodiesterase type 5 (PDE5) inhibitor |
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Mechanism of Action: | - Inhibits the breakdown of cyclic guanosine monophosphate (cGMP) by PDE5, leading to increased levels of cGMP in the corpus cavernosum of the penis
- Relaxes smooth muscle and increases blood flow to the penis, resulting in improved erectile function
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Use: | - Treatment of erectile dysfunction (ED)
- Treatment of benign prostatic hyperplasia (BPH)
- Treatment of pulmonary arterial hypertension (PAH)
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Side Effects: | - Headache
- Flushing
- Dyspepsia
- Nasal congestion
- Back pain
- Myalgia
- Vision changes (e.g. blurred vision, changes in color vision)
- Hearing loss
- Priapism
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Contraindications: | - Concomitant use with nitrates or nitric oxide donors
- Hypersensitivity to tadalafil or any component of the formulation
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Specialty: | - Urology
- Pulmonology
- Cardiology
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