Drug Name: | Tamoxifen |
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Drug Class: | Selective Estrogen Receptor Modulator (SERM) |
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Mechanism of Action: | - Binds to estrogen receptors and blocks estrogen from binding to them
- May also activate some estrogen receptors in certain tissues
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Use: | - Treatment of breast cancer
- Prevention of breast cancer in high-risk patients
- Reduction of breast cancer recurrence
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Side Effects: | - Hot flashes
- Vaginal dryness
- Nausea
- Fatigue
- Increased risk of blood clots and stroke
- Increased risk of endometrial cancer
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Contraindications: | - Pregnancy
- History of blood clots or stroke
- History of endometrial cancer
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Specialty: | |
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