Drug Name:Teriflunomide
Drug Class:Immunomodulator
Mechanism of Action:Inhibits dihydroorotate dehydrogenase, leading to decreased pyrimidine synthesis and inhibition of T-cell proliferation
Use:
  • Treatment of relapsing forms of multiple sclerosis
Side Effects:
  • Diarrhea
  • Elevated liver enzymes
  • Hair thinning or loss
  • Headache
  • Infections
  • Nausea
  • Respiratory tract infections
Contraindications:
  • Pregnancy
  • Severe hepatic impairment
  • Severe immunodeficiency
Specialty:
  • Neurology
  • Rheumatology