| Drug Name: | Thalidomide |
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| Drug Class: | Immunomodulatory agent |
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| Mechanism of Action: | Inhibits tumor necrosis factor-alpha (TNF-Ξ±) production, stimulates T-cell and natural killer (NK) cell activity, and inhibits angiogenesis |
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| Use: | - Treatment of multiple myeloma
- Treatment of erythema nodosum leprosum (ENL)
- Maintenance therapy for patients with recurrent or refractory multiple myeloma
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| Side Effects: | - Peripheral neuropathy
- Sedation
- Constipation
- Dizziness
- Rash
- Neutropenia
- Thromboembolism
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| Contraindications: | - Pregnancy
- Breastfeeding
- Hypersensitivity to thalidomide
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| Specialty: | - Hematology
- Oncology
- Dermatology
- Rheumatology
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