Drug Name:Tocilizumab
Drug Class:Monoclonal antibody
Mechanism of Action:Binds to and inhibits the interleukin-6 (IL-6) receptor, blocking IL-6 signaling
Use:
  • Rheumatoid arthritis
  • Giant cell arteritis
  • Systemic juvenile idiopathic arthritis
  • Cytokine release syndrome (associated with CAR-T cell therapy)
Side Effects:
  • Upper respiratory tract infections
  • Headache
  • Elevated liver enzymes
  • Hypertension
  • Infusion reactions
Contraindications:
  • Active infections
  • Hypersensitivity to tocilizumab or any component of the formulation
Specialty:
  • Rheumatology
  • Immunology
  • Oncology