| Drug Name: | Tolcapone |
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| Drug Class: | Catechol-O-methyltransferase (COMT) inhibitor |
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| Mechanism of Action: | - Inhibits the enzyme COMT, which breaks down dopamine in the brain
- Increases the levels of dopamine in the brain
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| Use: | - Used in the treatment of Parkinson's disease
- Improves motor symptoms and reduces 'off' time
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| Side Effects: | - Liver toxicity
- Diarrhea
- Nausea
- Vomiting
- Dizziness
- Headache
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| Contraindications: | - Hepatic impairment
- History of liver disease
- Concomitant use with other hepatotoxic drugs
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| Specialty: | |
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