| Drug Name: | Tranylcypromine |
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| Drug Class: | Monoamine oxidase inhibitor (MAOI) |
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| Mechanism of Action: | - Irreversible inhibition of monoamine oxidase (MAO) enzyme
- Increases levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain
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| Use: | - Major depressive disorder
- Social anxiety disorder
- Panic disorder
- Obsessive-compulsive disorder (OCD)
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| Side Effects: | - Hypertensive crisis (severe headache, palpitations, chest pain, sweating, nausea, vomiting, confusion, seizures)
- Insomnia
- Dry mouth
- Constipation
- Weight gain
- Sexual dysfunction
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| Contraindications: | - Concurrent use with other MAOIs, SSRIs, or certain other medications
- History of cerebrovascular disease, hypertension, or cardiovascular disease
- Liver or kidney disease
- Pheochromocytoma
- Tyramine-rich foods (aged cheese, cured meats, beer, wine, etc.)
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| Specialty: | |
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