Drug Name:Trastuzumab
Drug Class:Monoclonal antibody
Mechanism of Action:
  • Binds to HER2 receptor on cancer cells
  • Inhibits HER2 signaling pathway
  • Promotes antibody-dependent cellular cytotoxicity
Use:
  • Breast cancer
  • Gastric cancer
Side Effects:
  • Cardiotoxicity
  • Infusion reactions
  • Fatigue
  • Nausea
  • Diarrhea
Contraindications:
  • Hypersensitivity to trastuzumab
  • Pregnancy
  • Severe heart disease
Specialty:
  • Oncology
  • Hematology