Drug Name: | Vardenafil |
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Drug Class: | Phosphodiesterase type 5 (PDE5) inhibitor |
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Mechanism of Action: | - Inhibits the breakdown of cyclic guanosine monophosphate (cGMP) by PDE5, leading to increased blood flow to the penis
- Enhances the effects of nitric oxide (NO) released during sexual stimulation
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Use: | - Treatment of erectile dysfunction (ED)
- Improvement of sexual function in men with ED and diabetes or prostatectomy
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Side Effects: | - Headache
- Flushing
- Nasal congestion
- Dyspepsia
- Back pain
- Visual disturbances
- Hypotension
- Priapism
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Contraindications: | - Concomitant use with nitrates or nitric oxide donors
- Severe hepatic impairment
- Hypotension (systolic blood pressure < 90 mmHg)
- Recent stroke or myocardial infarction
- Hereditary degenerative retinal disorders
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Specialty: | - Urology
- Endocrinology
- Internal Medicine
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