Drug Name:Verapamil
Drug Class:Calcium channel blocker
Mechanism of Action:
  • Inhibits calcium ion influx into cardiac and smooth muscle cells
  • Relaxes coronary and systemic arteries
  • Decreases cardiac contractility and conduction velocity
Use:
  • Hypertension
  • Angina pectoris
  • Supraventricular tachycardia
  • Atrial fibrillation/flutter
  • Migraine prophylaxis
Side Effects:
  • Hypotension
  • Bradycardia
  • Constipation
  • Dizziness
  • Headache
  • Peripheral edema
Contraindications:
  • Severe hypotension
  • Sick sinus syndrome
  • Second- or third-degree AV block
  • Cardiogenic shock
  • Severe left ventricular dysfunction
Specialty:
  • Cardiology
  • Neurology