| Drug Name: | Xylazine |
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| Drug Class: | Alpha-2 adrenergic agonist |
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| Mechanism of Action: | - Binds to alpha-2 adrenergic receptors in the central nervous system
- Inhibits the release of norepinephrine and other neurotransmitters
- Produces sedation, analgesia, and muscle relaxation
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| Use: | - Sedation and analgesia in large animals (horses, cattle, etc.)
- Adjunct to anesthesia
- Treatment of colic in horses
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| Side Effects: | - Bradycardia
- Hypotension
- Respiratory depression
- Ataxia
- Muscle tremors
- Salivation
- Urinary retention
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| Contraindications: | - Animals with pre-existing heart, liver, or kidney disease
- Animals with hypovolemia or shock
- Animals with respiratory depression
- Pregnant animals
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| Specialty: | |
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