Drug Name: | quetiapine |
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Drug Class: | atypical antipsychotic |
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Mechanism of Action: | - blocks dopamine and serotonin receptors in the brain
- also has antagonistic effects on histamine and alpha-adrenergic receptors
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Use: | - treatment of schizophrenia
- treatment of bipolar disorder
- adjunctive treatment of major depressive disorder
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Side Effects: | - sedation
- weight gain
- dry mouth
- constipation
- dizziness
- orthostatic hypotension
- extrapyramidal symptoms
- increased risk of diabetes and hyperlipidemia
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Contraindications: | - hypersensitivity to quetiapine or any component of the formulation
- concomitant use with strong CYP3A4 inhibitors or inducers
- history of QT prolongation or cardiac arrhythmias
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Specialty: | |
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